相似文献
1
Sequence-specific DNA binding by the vnd/NK-2 homeodomain of Drosophila.
Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12721-6. doi: 10.1073/pnas.202461199. Epub 2002 Sep 13.
2
Identification and analysis of vnd/NK-2 homeodomain binding sites in genomic DNA.
Proc Natl Acad Sci U S A. 2005 May 17;102(20):7097-102. doi: 10.1073/pnas.0502261102. Epub 2005 May 3.
3
Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity.
Biochemistry. 1997 May 6;36(18):5372-80. doi: 10.1021/bi9620060.
4
The Nk-2 box of the Drosophila homeodomain protein, Vnd, contributes to its repression activity in a Groucho-dependent manner.
Mech Dev. 2007 Jan;124(1):1-10. doi: 10.1016/j.mod.2006.07.009. Epub 2006 Aug 2.
5
Kinetic analysis of Drosophila Vnd protein containing homeodomain with its target sequence.
BMB Rep. 2010 Jun;43(6):407-12. doi: 10.5483/bmbrep.2010.43.6.407.
6
Cardiac-specific Nkx2.5 homeodomain: conformational stability and specific DNA binding of Nkx2.5(C56S).
Biochemistry. 2005 Sep 20;44(37):12480-90. doi: 10.1021/bi050835s.
7
Mapping activation and repression domains of the vnd/NK-2 homeodomain protein.
Proc Natl Acad Sci U S A. 2004 Sep 7;101(36):13180-5. doi: 10.1073/pnas.0404775101. Epub 2004 Aug 30.
8
Structural basis of an embryonically lethal single Ala --> Thr mutation in the vnd/NK-2 homeodomain.
Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7412-6. doi: 10.1073/pnas.95.13.7412.
9
The three-dimensional structure of the vnd/NK-2 homeodomain-DNA complex by NMR spectroscopy.
J Mol Biol. 1999 Jun 11;289(3):529-45. doi: 10.1006/jmbi.1999.2774.
10
The vnd/NK-2 homeodomain: thermodynamics of reversible unfolding and DNA binding for wild-type and with residue replacements H52R and H52R/T56W in helix III.
Biochemistry. 2001 Apr 24;40(16):4923-31. doi: 10.1021/bi0022341.
引用本文的文献
1
Thyroid transcription factors in development, differentiation and disease.
Nat Rev Endocrinol. 2015 Jan;11(1):29-42. doi: 10.1038/nrendo.2014.186. Epub 2014 Oct 28.
2
Genome-wide screens for in vivo Tinman binding sites identify cardiac enhancers with diverse functional architectures.
PLoS Genet. 2013;9(1):e1003195. doi: 10.1371/journal.pgen.1003195. Epub 2013 Jan 10.
3
Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target.
Genes Dev. 2013 Jan 15;27(2):197-210. doi: 10.1101/gad.203208.112.
4
The alternative protein isoform NK2B, encoded by the vnd/NK-2 proneural gene, directly activates transcription and is expressed following the start of cells differentiation.
Nucleic Acids Res. 2011 Jul;39(13):5401-11. doi: 10.1093/nar/gkr121. Epub 2011 Mar 21.
5
Novel computational analysis of protein binding array data identifies direct targets of Nkx2.2 in the pancreas.
BMC Bioinformatics. 2011 Feb 25;12:62. doi: 10.1186/1471-2105-12-62.
6
The HMX/NKX homeodomain protein MLS-2 specifies the identity of the AWC sensory neuron type via regulation of the ceh-36 Otx gene in C. elegans.
Development. 2010 Mar;137(6):963-74. doi: 10.1242/dev.044719. Epub 2010 Feb 11.
7
Identification and analysis of vnd/NK-2 homeodomain binding sites in genomic DNA.
Proc Natl Acad Sci U S A. 2005 May 17;102(20):7097-102. doi: 10.1073/pnas.0502261102. Epub 2005 May 3.
8
Mapping activation and repression domains of the vnd/NK-2 homeodomain protein.
Proc Natl Acad Sci U S A. 2004 Sep 7;101(36):13180-5. doi: 10.1073/pnas.0404775101. Epub 2004 Aug 30.
9
Mutations that affect the ability of the vnd/NK-2 homeoprotein to regulate gene expression: transgenic alterations and tertiary structure.
Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3119-24. doi: 10.1073/pnas.0438043100. Epub 2003 Mar 7.
本文引用的文献
1
Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation.
Genes Dev. 2002 May 15;16(10):1234-46. doi: 10.1101/gad.222902.
2
The Sox-domain containing gene Dichaete/fish-hook acts in concert with vnd and ind to regulate cell fate in the Drosophila neuroectoderm.
Development. 2002 Mar;129(5):1165-74. doi: 10.1242/dev.129.5.1165.
3
Partial deficiency of thyroid transcription factor 1 produces predominantly neurological defects in humans and mice.
J Clin Invest. 2002 Feb;109(4):469-73. doi: 10.1172/JCI14192.
4
Regulated vnd expression is required for both neural and glial specification in Drosophila.
J Neurobiol. 2002 Feb 5;50(2):118-36. doi: 10.1002/neu.10022.
5
A triad of serum response factor and the GATA and NK families governs the transcription of smooth and cardiac muscle genes.
J Biol Chem. 2002 Mar 1;277(9):7308-17. doi: 10.1074/jbc.M111824200. Epub 2001 Dec 14.
6
Nkx2.5 and Nkx2.6, homologs of Drosophila tinman, are required for development of the pharynx.
Mol Cell Biol. 2001 Jul;21(13):4391-8. doi: 10.1128/MCB.21.13.4391-4398.2001.
7
The human, but not rat, dio2 gene is stimulated by thyroid transcription factor-1 (TTF-1).
Mol Endocrinol. 2001 Jan;15(1):112-24. doi: 10.1210/mend.15.1.0579.
8
Intramolecular control of transcriptional activity by the NK2-specific domain in NK-2 homeodomain proteins.
Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9443-8. doi: 10.1073/pnas.97.17.9443.
9
DNA-binding sequence of the human prostate-specific homeodomain protein NKX3.1.
Nucleic Acids Res. 2000 Jun 15;28(12):2389-95. doi: 10.1093/nar/28.12.2389.
10
Vnd/nkx, ind/gsh, and msh/msx: conserved regulators of dorsoventral neural patterning?
Curr Opin Neurobiol. 2000 Feb;10(1):63-71. doi: 10.1016/s0959-4388(99)00049-5.
Zotero 插件