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[同一颈椎水平的相关脑膜瘤和神经纤维瘤,无神经纤维瘤病临床体征:病例报告]

[Associated meningioma and neurofibroma at the same cervical level without clinical signs of neurofibromatosis: case report].

作者信息

Hokari Masaaki, Hida Kazutoshi, Ishii Nobuaki, Seki Toshitaka, Iwasaki Yoshinobu, Nakamura Nishio

机构信息

Department of Neurosurgery, Hokkaido University Graduate School of Medicine, North 15, West 7, Kita-ku, Sapporo, Hokkaido 060-8638, Japan.

出版信息

No Shinkei Geka. 2002 Sep;30(9):953-7.

Abstract

A 59-year-old woman presented with a history of progressive clumsiness and numbness in both hands. MRI suggested a solid mass extending, from the intradural extramedullary, extradurally at the left C1/2 level. However, intraoperative findings revealed the both the intradural tumor and the extradural tumor existed separately. Histopathological findings revealed coincident meningioma (intradural) and neurofibroma (extradural). These lesions were not associated with neurofibromatosis, and the patient did not have other tumors in either the brain or at other levels of the spine. The occurrence of different types of spinal tumors without clinical signs of neurofibromatosis is very rare. Only five cases have been reported in the literature. To our knowledge, this is the first case of occurrence of different types of spinal tumors at the same level.

摘要

一名59岁女性,有双手进行性笨拙和麻木的病史。磁共振成像(MRI)显示一个实性肿块,从硬脊膜内髓外延伸至左侧C1/2水平的硬膜外。然而,术中发现硬脊膜内肿瘤和硬膜外肿瘤是分开存在的。组织病理学检查结果显示同时存在脑膜瘤(硬脊膜内)和神经纤维瘤(硬膜外)。这些病变与神经纤维瘤病无关,且患者在脑部或脊柱其他节段均未发现其他肿瘤。在无神经纤维瘤病临床体征的情况下出现不同类型的脊柱肿瘤非常罕见。文献中仅报道过5例。据我们所知,这是首例在同一节段出现不同类型脊柱肿瘤的病例。

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