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采用钛环和鼻中隔软骨治疗气管狭窄

Management of tracheal stenosis with a titanium ring and nasal septal cartilage.

作者信息

Aidonis A, Nikolaou A, Bourikas Z, Aidonis I

机构信息

Department of Otolaryngology, Papanikolaou General Hospital, Thessaloniki, Greece.

出版信息

Eur Arch Otorhinolaryngol. 2002 Sep;259(8):404-8. doi: 10.1007/s00405-002-0483-9. Epub 2002 May 24.

Abstract

Surgical management of subglottic laryngeal and upper tracheal stenosis remains a formidable challenge. The significant number of proposed techniques only highlights the difficulties associated with effectively managing this problem. Between 1996 and 1999, seven patients with stenosis of the upper trachea were treated. The stenosis resulted from long-term intubation during intensive-care hospitalization in five patients and from tracheotomy complications in the other two. Six patients were male and one female, their ages ranging between 13 and 60 years. The mean postoperative observation period was 3 years (1.5-4.5 years). In all patients, the stenosis exclusively involved the upper tracheal segment, measuring from 2 to 5 cm in length. The stenotic area of the trachea is exposed, and the local application of a solution of mitomicin C for a duration of 4 min is performed. A graft consisting of cartilage and mucosa is harvested from the nasal septum and is fixed with sutures to a titanium semi-ring. After the fixation of the graft on the ring, the entire construct is placed on the stenosed segment of the exposed trachea. The graft must cover the anterior exposed face of the trachea with the lateral members of the semicircular titanium ring adjacent to the lateral walls of the trachea, externally. The lateral tracheal walls are attracted laterally with sutures and are attached on the edges of the semicircular titanium ring. Four of the patients in whom no tracheotomy had been performed preoperatively needed none at all intraoperatively, and they were decannulated normally at the end of the procedure. Tracheotomy was deemed necessary for one patient's safety and was maintained for 7 days. In one patient with a preoperative tracheotomy, the point of the tracheotomy was displaced lower on the trachea and was maintained there for 7 days. The course of management described here and employed on seven patients involves a safe surgical procedure with excellent results. The placement of the titanium ring offers very good support for the graft and maintains the patency of the tracheal lumen. The main reasons for the failure of techniques using only cartilage grafts are therefore avoided. The number of cases presented here is certainly too small to establish definite conclusions; however, the initial results are extremely satisfying and urge us to suggest the use of this method in indicated cases.

摘要

声门下喉和气管上段狭窄的外科治疗仍然是一项艰巨的挑战。众多提出的技术仅凸显了有效处理这一问题的困难。1996年至1999年间,对7例气管上段狭窄患者进行了治疗。5例患者的狭窄是由于重症监护住院期间长期插管所致,另外2例是气管切开术并发症所致。6例为男性,1例为女性,年龄在13至60岁之间。术后平均观察期为3年(1.5至4.5年)。所有患者的狭窄均仅累及气管上段,长度为2至5厘米。暴露气管狭窄区域,局部应用丝裂霉素C溶液4分钟。从鼻中隔获取一块由软骨和黏膜组成的移植物,并用缝线固定在一个钛半环上。将移植物固定在环上后,将整个结构放置在暴露的气管狭窄段上。移植物必须覆盖气管的前暴露面,半圆形钛环的侧部构件在外部与气管侧壁相邻。用缝线将气管侧壁向外侧牵拉,并附着在半圆形钛环的边缘。术前未行气管切开术的4例患者术中根本不需要气管切开术,术后正常拔管。为了1例患者的安全,认为有必要进行气管切开术,并维持了7天。1例术前有气管切开术的患者,气管切开部位在气管上较低位置移位,并在该处维持了7天。这里描述并应用于7例患者的治疗过程涉及一种安全的手术方法,效果极佳。钛环的放置为移植物提供了很好的支撑,并维持了气管腔的通畅。因此避免了仅使用软骨移植物技术失败的主要原因。这里展示的病例数量当然太少,无法得出明确结论;然而,初步结果非常令人满意,并促使我们建议在适应证病例中使用这种方法。

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