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兔手术划痕后气管对细菌纤维素敷料的炎症反应

Tracheal inflammatory response to bacterial cellulose dressing after surgical scarification in rabbits.

作者信息

Panerari Angelo D'urso, Costa Henrique Olival, Souza Flavia Coelho de, Castro Marília, Silva Leonardo da, Sousa Neto Osmar Mesquita de

机构信息

Santa Casa de São Paulo, Maringá, Paraná.

出版信息

Braz J Otorhinolaryngol. 2008 Jul-Aug;74(4):512-22. doi: 10.1016/s1808-8694(15)30597-8.

DOI:10.1016/s1808-8694(15)30597-8
PMID:18852976
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9442072/
Abstract

UNLABELLED

Exuberant scarring tissue formation is among the failure causes of tracheal stenosis surgery. Dressings that could avoid such reaction could be very helpful in these cases. Bacterial cellulose, produced by acetobacter xylinun can be useful in these cases. There are no studies in the laryngotracheal region.

AIM

To assess subglottic tissue response in rabbits after scarification and placement of cellulose dressing, and comparing it to a control group.

STUDY DESIGN

Experimental.

MATERIALS AND METHODS

26 rabbits underwent laryngotracheal scarification, received the dressing and were compared to the control group. We established four follow up periods. Laryngotracheal specimens underwent histological exam and the results were statistically assessed.

RESULTS

The study group had statistically similar results when compared to the control group in the following parameters: vascular congestion, purulent oozing, acute inflammation, epithelial integrity, fibrous proliferation and granulous proliferation.

CONCLUSION

We did not observe differences between the study and control groups as far as inflammation and scarring are concerned. There were no inflammatory signs associated with the use of the cellulose membrane that did no occur because of surgery.

摘要

未标注

过度的瘢痕组织形成是气管狭窄手术失败的原因之一。能够避免这种反应的敷料在这些病例中可能非常有帮助。木醋杆菌产生的细菌纤维素在这些病例中可能有用。目前尚无关于喉气管区域的研究。

目的

评估兔声门下组织在划痕并放置纤维素敷料后的反应，并与对照组进行比较。

研究设计

实验性研究。

材料与方法

26只兔接受喉气管划痕，使用敷料，并与对照组进行比较。我们设定了四个随访期。对喉气管标本进行组织学检查，并对结果进行统计学评估。

结果

在以下参数方面，研究组与对照组相比具有统计学上相似的结果：血管充血、脓性渗出、急性炎症、上皮完整性、纤维增生和颗粒增生。

结论

就炎症和瘢痕形成而言，我们未观察到研究组与对照组之间存在差异。使用纤维素膜未出现因手术未发生的炎症迹象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/415962b9b4a6/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/7cc89b438780/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/d507e510826c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/230115bb563a/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/6d27f11c6051/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/ebab6d261b13/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/752561923c58/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/16b261d319c8/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/594d64d57bdf/gr11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/b48f80e59ae1/gr12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/424c59c61612/gr13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/5f3c909fa049/gr14.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/830c0c03a341/gr15.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/a14d6fd7677e/gr16.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/b300a8dd91c1/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/c5b5d435bc9e/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/415962b9b4a6/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/7cc89b438780/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/d507e510826c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/230115bb563a/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/6d27f11c6051/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/ebab6d261b13/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/752561923c58/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/16b261d319c8/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/594d64d57bdf/gr11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/b48f80e59ae1/gr12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/424c59c61612/gr13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/5f3c909fa049/gr14.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/830c0c03a341/gr15.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/a14d6fd7677e/gr16.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/b300a8dd91c1/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/c5b5d435bc9e/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a55d/9442072/415962b9b4a6/gr6.jpg

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