Suppr超能文献

[鼻窦炎继发硬膜下积脓:4例儿科病例]

[Subdural empyema secondary to sinusitis: four pediatric cases].

作者信息

Oliveira-Monteiro J P, Duarte-Teles A L, Silva-Gonçalves M L, Carmo-Fonseca M J

机构信息

Universidad de Neuropediatría y Desarrollo. Servicio de Pediatría. Hospital Garcia de Orta, Almada, Portugal.

出版信息

Rev Neurol. 2002;35(4):331-6.

Abstract

INTRODUCTION

Perinasal sinus infections is a common and benign condition in most pediatric cases. Because of the widespread use of antibiotics, intracranial extension of sinusitis is rarely seen today. Nevertheless, the clinician must be aware of the gravity of this condition, because late recognition and delay in treatment can increase mortality and morbidity. The authors made a retrospective study of pediatric patients admitted to Garcia de Orta Hospital between 1996 and 2001 with the diagnosis of subdural empyema and sinusitis.

CASE REPORTS

Four patients were identified, with ages between 9 and 13 years. Prodromal manifestations of sinusitis were present in all, followed several days later by headaches, fever, vomiting and neurological abnormalities. Two patients presented in the emergency department with an acute confusional state and a non convulsive status epilepticus. The other two patients had a longer duration of disease, severe deterioration of consciousness and focal neurologic signs. Medical treatment was started in all cases at admission, but none improved significantly before being submitted to surgical intervention, which was repeated several times in two patients. Streptococcus milleri and anaerobic organisms were isolated. There was no mortality and global evolution was favorable, with a median follow up of 32 months.

CONCLUSIONS

Clinical presentation of subdural empyema can be relatively inespecific, requiring a high degree of suspicion. Facing a young adolescent with fever of unknown origin associated with any neurological abnormality and previous history of sinusitis, neuroradiological investigation shoul be asked. Early diagnosis and treatment are the mainstays of successful outcome.

摘要

引言

在大多数儿科病例中,鼻周窦感染是一种常见的良性病症。由于抗生素的广泛使用,如今鼻窦炎向颅内蔓延的情况已很少见。然而,临床医生必须意识到这种病症的严重性,因为识别延迟和治疗延误可能会增加死亡率和发病率。作者对1996年至2001年期间入住加西亚·德奥尔塔医院、诊断为硬膜下积脓和鼻窦炎的儿科患者进行了回顾性研究。

病例报告

共确定了4例患者,年龄在9至13岁之间。所有患者均有鼻窦炎的前驱表现,数天后出现头痛、发热、呕吐和神经功能异常。2例患者在急诊科表现为急性意识模糊状态和非惊厥性癫痫持续状态。另外2例患者病程较长,意识严重恶化并伴有局灶性神经体征。所有病例入院时均开始药物治疗,但在接受手术干预之前均无明显改善,其中2例患者进行了多次手术。分离出米勒链球菌和厌氧菌。无死亡病例,总体预后良好,中位随访时间为32个月。

结论

硬膜下积脓的临床表现可能相对不具特异性,需要高度怀疑。面对一名有不明原因发热、伴有任何神经功能异常且有鼻窦炎既往史的青少年,应进行神经放射学检查。早期诊断和治疗是成功治疗的关键。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验