Sproule Beth A, Naranjo Claudio A, Türksen I Burhan
Centre for Addiction and Mental Health, 33 Russell Street, Ontario, M5S 2S1, Toronto, Canada.
Trends Pharmacol Sci. 2002 Sep;23(9):412-7. doi: 10.1016/s0165-6147(02)02055-2.
Fuzzy pharmacology is a term coined to represent the application of fuzzy logic and fuzzy set theory to pharmacological problems. Fuzzy logic is the science of reasoning, thinking and inference that recognizes and uses the real world phenomenon that everything is a matter of degree. It is an extension of binary logic that is able to deal with complex systems because it does not require crisp definitions and distinctions for the system components. In pharmacology, fuzzy modeling has been used for the mechanical control of drug delivery in surgical settings, and work has begun evaluating its use in other pharmacokinetic and pharmacodynamic applications. Fuzzy pharmacology is an emerging field that, based on these initial explorations, warrants further investigation.
模糊药理学是一个新造术语，用于表示将模糊逻辑和模糊集理论应用于药理学问题。模糊逻辑是一门关于推理、思考和推断的科学，它认识并运用现实世界中一切都是程度问题这一现象。它是二值逻辑的扩展，能够处理复杂系统，因为它不需要对系统组件进行清晰的定义和区分。在药理学中，模糊建模已用于手术环境中药物递送的机械控制，并且已经开始评估其在其他药代动力学和药效学应用中的用途。基于这些初步探索，模糊药理学是一个新兴领域，值得进一步研究。
