Platz T, Kim I-H, Engel U, Kieselbach A, Mauritz K-H
Klinik Berlin, Abteilung für Neurologische Rehabilitation der Freien Universität Berlin am Universitätsklinikum Benjamin Franklin, Berlin, Germany.
Restor Neurol Neurosci. 2002;20(1-2):21-35.
Receiving the Arm Ability Training for three weeks improves motor function among stroke patients with mild arm paresis. There is, however, a considerable variability in recovery among patients receiving the Arm Ability Training. The study investigated whether intersubject differences in movement-related electric brain activity explain the variability in motor recovery.
In a sample of 9 patients receiving the Arm Ability Training both motor performance using a standardised arm function test (TEMPA) and movement-related electric brain activity, i.e. slow cortical potentials (DC) as well as event-related desynchronisation of alpha (alpha-ERD) and beta activity (beta-ERD), were assessed before the Arm Ability Training was started. Stepwise multiple regression was used to establish the best predictive model for motor improvement scores (TEMPA difference from pre to post test three weeks later).
Stepwise multiple regression indicated that electric brain activity during movement preparation explained the variance of motor improvement scores completely. Further, electric brain activity during movement as well as baseline motor performance accounted each for 50% of the variance of motor improvement scores.
Activation of sensorimotor areas during movement preparation and deactivation of other cortical areas during movement execution seem to be factors that predict a favourable outcome after training.
接受为期三周的手臂能力训练可改善轻度手臂麻痹的中风患者的运动功能。然而，接受手臂能力训练的患者恢复情况存在相当大的差异。该研究调查了与运动相关的脑电活动的个体间差异是否能解释运动恢复的变异性。
在9名接受手臂能力训练的患者样本中，在开始手臂能力训练之前，使用标准化手臂功能测试（TEMPA）评估运动表现，并评估与运动相关的脑电活动，即慢皮层电位（DC）以及α波（α-ERD）和β波活动（β-ERD）的事件相关去同步化。采用逐步多元回归建立运动改善分数（三周后测试前与测试后TEMPA的差异）的最佳预测模型。
逐步多元回归表明，运动准备期间的脑电活动完全解释了运动改善分数的方差。此外，运动期间的脑电活动以及基线运动表现各占运动改善分数方差的50%。
运动准备期间感觉运动区域的激活以及运动执行期间其他皮层区域的失活似乎是预测训练后良好结果的因素。
