Saadoun S, Papadopoulos M C, Davies D C, Bell B A, Krishna S
Department of Infectious Diseases, St. George's Hospital Medical School, Cranmer Terrace, Tooting, London SW17 0RE, UK.
Br J Cancer. 2002 Sep 9;87(6):621-3. doi: 10.1038/sj.bjc.6600512.
Aquaporin 1 is a water channel protein. There was little aquaporin 1 immunoreactivity in normal brain parenchyma. In astrocytomas, aquaporin 1 was expressed in microvessel endothelia and neoplastic astrocytes. In metastatic carcinomas, aquaporin 1 was present in microvessel endothelia and reactive astrocytes. Aquaporin 1 may participate in the formation of brain tumour oedema.
水通道蛋白1是一种水通道蛋白。在正常脑实质中几乎没有水通道蛋白1免疫反应性。在星形细胞瘤中，水通道蛋白1在微血管内皮细胞和肿瘤性星形胶质细胞中表达。在转移性癌中，水通道蛋白1存在于微血管内皮细胞和反应性星形胶质细胞中。水通道蛋白1可能参与脑肿瘤水肿的形成。
