路边土壤中的诱变活性。

Mutagenic activity in roadside soils.

作者信息

Tsukatani Hiroko, Tanaka Yoshito, Sera Nobuyuki, Shimizu Nobuhiro, Kitamori Shigeji, Inoue Naohide

机构信息

Fukuoka Institute of Health and Environmental Sciences, 39 Mukaizano, Dazaifu, Fukuoka 818-0135, Japan.

出版信息

J Toxicol Sci. 2002 Aug;27(3):183-9. doi: 10.2131/jts.27.183.

DOI:10.2131/jts.27.183

PMID:12238142

Abstract

Mutagenicity of soils sampled at median strips, roadsides and a park neighboring arterial roads in Kurume City was determined by Ames test. Organic extracts of soils were mutagenic in strains TA98, TA100, YG1041 and YG1042 with and without S9mix. No sample showed mutagenic responses in strains YG3003 or YG7108. Extracts from soils of median strips and beside intersections showed higher mutagenicity and concentrations of PAHs and heavy metals than others, and mutagenic activity of soils correlated significantly with concentrations of PAHs and heavy metals. However, PAHs accounted for less than 12% of total mutagenicity in strains TA98 and TA100 of soil extracts. These extracts showed much higher mutagenicity in YG strains than in TA strains. The results indicate that these soils may be polluted with nitroarenes and aromatic amines.

摘要

通过艾姆斯试验测定了久留米市中央分隔带、路边以及与主干道相邻公园采集的土壤的致突变性。土壤的有机提取物在有和没有S9混合液的情况下，对TA98、TA100、YG1041和YG1042菌株均具有致突变性。没有样品在YG3003或YG7108菌株中表现出致突变反应。中央分隔带和交叉路口旁土壤的提取物比其他地方的提取物表现出更高的致突变性以及多环芳烃和重金属浓度，并且土壤的致突变活性与多环芳烃和重金属浓度显著相关。然而，在土壤提取物的TA98和TA100菌株中，多环芳烃占总致突变性的比例不到12%。这些提取物在YG菌株中的致突变性比在TA菌株中高得多。结果表明，这些土壤可能受到硝基芳烃和芳香胺的污染。