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城市人群中心肌梗死:来自较贫困居民区的患者长期预后更差。

Myocardial infarction in an urban population: worse long term prognosis for patients from less affluent residential areas.

作者信息

Tydén P, Hansen O, Engström G, Hedblad B, Janzon L

机构信息

Department of Community Medicine, Malmö University Hospital, Lund University, Malmö, Sweden.

出版信息

J Epidemiol Community Health. 2002 Oct;56(10):785-90. doi: 10.1136/jech.56.10.785.

Abstract

STUDY OBJECTIVE

The objective in this follow up study from the Malmö myocardial infarction register has been to assess whether long term survival following discharge after first myocardial infarction has any relation with the socioeconomic environment and to assess to what extent intra-urban differences in mortality from ischaemic heart disease can be accounted for by covariance with long term survival following discharge after acute myocardial infarction.

DESIGN

Register based surveillance study.

SETTING

Seventeen residential areas in the city of Malmö, Sweden.

PARTICIPANTS

The cohort contains all 2931 male and 2083 female patients with myocardial infarction who were discharged for the first time between 1986-95 from Malmö University Hospital.

MAIN RESULTS

During the on average 4.9 years of follow up 55% of the patients died. The sex adjusted and age adjusted all cause mortality rate/1000 patient years ranged between residential areas from 85.5 to 163.6. The area specific relative risk of death after discharge was associated with a low socioeconomic score, r=-0.56, p=0.018. Major risk factors for cardiovascular disease were more prevalent in areas with low socioeconomic score and low rates of survival. Of the intra-urban differences in mortality from ischaemic heart disease, 41% could be accounted for by differences with regard to the survival rate after discharge.

CONCLUSIONS

The results are compatible with the hypothesis that the socioeconomic environment plays an important part in the survival rate of patients with myocardial infarction. To assess the preventive potential, the extent to which socioeconomic circumstances covary with severity of disease, respectively with the use and compliance with secondary preventive measures, needs to be evaluated.

摘要

研究目的

这项来自马尔默心肌梗死登记处的随访研究旨在评估首次心肌梗死后出院后的长期生存率是否与社会经济环境有关,并评估城市内部缺血性心脏病死亡率的差异在多大程度上可由急性心肌梗死后出院后的长期生存率的协变量来解释。

设计

基于登记处的监测研究。

地点

瑞典马尔默市的17个居民区。

参与者

该队列包括1986年至1995年间首次从马尔默大学医院出院的所有2931名男性和2083名女性心肌梗死患者。

主要结果

在平均4.9年的随访期间,55%的患者死亡。按性别和年龄调整后的全因死亡率/每1000患者年在不同居民区之间从85.5到163.6不等。出院后特定区域的死亡相对风险与低社会经济评分相关,r = -0.56,p = 0.018。心血管疾病的主要危险因素在社会经济评分低和生存率低的地区更为普遍。在城市内部缺血性心脏病死亡率的差异中,41%可由出院后生存率的差异来解释。

结论

结果与社会经济环境在心肌梗死患者生存率中起重要作用的假设相符。为了评估预防潜力,需要评估社会经济状况分别与疾病严重程度、二级预防措施的使用和依从性之间的共变程度。

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