Guney Ercihan, Yigitbasi Orhan Gazi, Balkanli Sülegman, Canoz Ozlem M
Otorhinolaryngology-Head and Neck Surgery Department and the Pathology Department, Faculty of Medicine, Erciyes University, Kayseri, Turkey.
Am J Otolaryngol. 2002 Sep-Oct;23(5):293-6. doi: 10.1053/ajot.2002.124554.
A 63-year-old man presented with malignant fibrous histiocytoma of the larynx occurring 16 years after radiation treatment for squamous cell carcinoma of the larynx. Postirradiation sarcoma of the larynx is an unusual tumor. The location, the histopathologic and immunohistochemical appearance of the tumor, and the time elapsed since the initial treatment make it probable that this tumor is associated with prior radiation treatment. The possibility of postirradiation sarcomas after radiation therapy should not be a major factor influencing treatment decisions in the patients with head and neck cancer. Wide surgical resection of the tumor seems to be an efficient means in the management of this tumor.
一名63岁男性患者，在接受喉鳞状细胞癌放射治疗16年后出现喉恶性纤维组织细胞瘤。喉放疗后肉瘤是一种罕见肿瘤。肿瘤的位置、组织病理学和免疫组化表现，以及距初始治疗后的时间，使得该肿瘤很可能与先前的放射治疗有关。放射治疗后发生放疗后肉瘤的可能性不应成为影响头颈癌患者治疗决策的主要因素。广泛手术切除肿瘤似乎是治疗该肿瘤的有效方法。
