去甲丙咪嗪的放射免疫测定法
Radioimmunoassay for desmethylimipramine.
作者信息
Spector S, Spector N L, Almeida M P
出版信息
Psychopharmacol Commun. 1975;1(4):421-9.
PMID:1224010
Abstract
This paper describes the production of antibodies against demethyl-imipramine (DMI). By using antisera, a radioimmunoassay was developed capable of detecting 0.2 ng of DMI which is linear up to 25 ng. The assay has been applied for the measurement of DMI in rat plasma and brain. The assay might find application especially when only limited amounts of blood, plasma or tissue are available.
摘要
本文描述了抗去甲基丙咪嗪（DMI）抗体的制备。通过使用抗血清，开发了一种放射免疫测定法，该方法能够检测低至0.2 ng的DMI，在25 ng范围内呈线性。该测定法已应用于大鼠血浆和脑组织中DMI的测量。特别是在仅有少量血液、血浆或组织可用时，该测定法可能会有应用价值。
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