Furlanetto Alberto, Dei Tos Angelo Paolo
Department of Pathology, Treviso General Hospital, 31100 Treviso, Italy.
Virchows Arch. 2002 Sep;441(3):296-8. doi: 10.1007/s00428-002-0668-z. Epub 2002 Jul 10.
We report a case of squamous-cell carcinoma arising in a ciliated hepatic foregut cyst that occurred in a 21-year-old man. The cystic lesion was first discovered during childhood with no further follow-up. Following important weight loss over several months, the patient was admitted to our hospital where a CT scan showed a cystic and solid mass in segments V and VI of the liver involving the transverse mesocolon and the gastric antrum. A right hepatectomy with en-bloc right hemicolectomy and partial gastrectomy was performed. Gross examination showed a partially cystic liver mass with a maximum dimension of 10 cm infiltrating the large bowel wall. Microscopically, it was a poorly differentiated squamous-cell carcinoma arising from the wall of a liver cyst lined by a ciliated, pseudostratified columnar epithelium. Hepatic foregut cysts are uncommon, congenital, benign lesions that, when discovered, deserve careful clinical follow-up as malignant transformation, albeit exceptional, is possible.
我们报告一例纤毛肝前肠囊肿发生鳞状细胞癌的病例，患者为一名21岁男性。该囊性病变在儿童期首次发现，之后未进一步随访。在数月内体重显著减轻后，患者入住我院，CT扫描显示肝脏Ⅴ段和Ⅵ段有一个囊实性肿块，累及横结肠系膜和胃窦。遂行右肝切除术，同时整块切除右半结肠和部分胃。大体检查显示一个最大直径为10cm的部分囊性肝脏肿块，浸润大肠壁。显微镜下，这是一种低分化鳞状细胞癌，起源于一个由纤毛假复层柱状上皮衬里的肝囊肿壁。肝前肠囊肿是罕见的先天性良性病变，一旦发现，尽管恶变可能性极小，但仍值得仔细的临床随访。
