Knöbel H, Becker K
Z Gastroenterol. 1975 Oct;13(6):583-7.
15 patients with a histologically and/or peritoneoscopically proven cirrhosis of the liver were treated for four weeks with 200 mg metenolonenanthate (Depot-Primobolan) per week. Before and after the treatment the intravascular and extravascular pool and daily turnover of albumin were measured with 125J-albumin. All patients had a well "compensated" cirrhosis. The only significant difference between the values of the cirrhotic patients and those of a control group of patients was a reduction of the albumin turn-over. The anabolic steroid enlarged the turn-over, the effect was the more pronounced the more pronounced the more the turn over was diminished before the treatment.
15例经组织学和/或腹腔镜检查证实为肝硬化的患者，每周接受200毫克美睾酮庚酸酯（长效康力龙）治疗，为期四周。治疗前后，用125I-白蛋白测量血管内和血管外白蛋白池及白蛋白的每日周转率。所有患者均为病情“代偿良好”的肝硬化患者。肝硬化患者与对照组患者的数值之间唯一显著差异是白蛋白周转率降低。合成代谢类固醇增加了周转率，治疗前周转率降低越明显，其效果就越显著。
