Grzycki S, Tochman A
Z Mikrosk Anat Forsch. 1975;89(2):219-30.
During the experimental investigations special attention was paid to the orthomorphology of the ultrastructure of cardiac muscle intercalated disc in a rat. The contact junction between the cellular membranes of adjacent cells and intercellular spaces are typical for the cardiac muscle intercalated disc. Attention was paid to the three zone system of the junctions, namely: 1. nexus (zonula occludens), 2. fascia adherens (zonula adherens) and 3. macula adherens (similar to the desmosome). Apart from this the cell membranes adjacent to the cells may form digital indentations. A single injection of adrenaline in a dose of 2.4 mg/kg causes sinuate widenings of the intercellular space, but only in the zone of the fascia adherens. The structure of the nexuses and maculae adherentes is unchanged during this time.
在实验研究过程中,特别关注了大鼠心肌闰盘超微结构的正常形态学。相邻细胞的细胞膜之间的接触连接和细胞间隙是心肌闰盘的典型特征。研究人员关注了连接的三区系统,即:1. 缝隙连接(紧密连接带),2. 黏合带(黏着连接带)和3. 黏着斑(类似于桥粒)。除此之外,相邻细胞的细胞膜可能会形成指状凹陷。单次注射剂量为2.4 mg/kg的肾上腺素会导致细胞间隙呈正弦状增宽,但仅在黏合带区域出现。在此期间,缝隙连接和黏着斑的结构保持不变。