Welt K, Scheller W, Schippel K, Schippel G
Z Mikrosk Anat Forsch. 1975;89(2):327-39.
This paper continues former ultrastructural investigations about fetal development of capillaries in the muscle anlage of the fore limb of white rats. Present investigations deal with postnatal ultrastructural changes of the capillaries of the triceps muscle of rats from the 4th up to the 23rd day p.p. Counting of the capillaries with light and electron microscope reveal a linear increase of the capillary to fiber ratio in this period proportional to the growth of the muscle. Related to a defined area however the number of capillaries remains constantly. Ultrastructural changes of capillaries consist in further flattening of the endothelial profiles, decrease in number or organelles (mitochondria and endoplasmic reticulum), while the number of pinocytotic vesicles remains highmthe endothelial joints become less interdigitated, the basement membrane shows an increase in density leading to a temporary decrease in thickness. Since the 9th postnatal day all of the capillaries including buds closely border upon the muscle fibres. The distance between endothelium and myofiber diminishes up to 0,1 mum.
本文延续了之前关于大白鼠前肢肌肉原基中毛细血管胎儿发育的超微结构研究。目前的研究涉及出生后第4天至第23天大鼠肱三头肌毛细血管的超微结构变化。用光镜和电镜对毛细血管进行计数发现,在此期间毛细血管与纤维的比例呈线性增加,与肌肉生长成正比。然而,相对于特定区域,毛细血管的数量保持恒定。毛细血管的超微结构变化包括内皮轮廓进一步变平、细胞器(线粒体和内质网)数量减少,而吞饮小泡的数量仍然很高;内皮连接的相互交错减少,基底膜密度增加导致厚度暂时减小。自出生后第9天起,所有毛细血管包括芽都紧密毗邻肌纤维。内皮与肌纤维之间的距离缩小至0.1微米。