Welt K, Scheller W, Schippel G, Schippel K
Z Mikrosk Anat Forsch. 1978;92(3):465-78.
The capillarisation of the triceps muscle of white rats was investigated with light and electron microscope up to the age of 20th month. During the postnatal development the capillary to fiber ratio corresponding to the increase of the number of capillaries is well adapted to an exponential function. The rapid increase of thickness of the muscle fibers causes a decrease of the number of capillaries per area unit. After the third week of life with histochemical methods the differentiation of muscle fiber types is possible, well correlated to the beginning of motoric activity. Ultrastructural alterations of the muscle capillaries consist in a flattening of the endothelium within the first month of postnatal life, a decrease of the content of organelles, a high degree of vesiculation and a continuous thickining of the basement membrane up to more than 100 nm. The interendothelial clefts show a simple structure containing 1--2 junctional zones and only few dilatations.
用光学显微镜和电子显微镜对20月龄大白鼠肱三头肌的毛细血管化进行了研究。在出生后的发育过程中，对应于毛细血管数量增加的毛细血管与纤维比例很好地符合指数函数。肌纤维厚度的快速增加导致单位面积内毛细血管数量减少。出生后第三周后，用组织化学方法可以区分肌纤维类型，这与运动活动的开始密切相关。肌肉毛细血管的超微结构改变包括出生后第一个月内内皮细胞变平、细胞器含量减少、高度囊泡化以及基底膜持续增厚至超过100纳米。内皮细胞间裂显示出简单的结构，包含1 - 2个连接区，仅有少量扩张。
