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自体灌注多器官制备。II. 自体灌注器官中的微循环。

Autoperfused multi-organ preparations. II. Microcirculation in the autoperfused organs.

作者信息

Szmolenszky T, Hammágyi G y, Röth E, Täorök B

出版信息

Acta Chir Acad Sci Hung. 1975;16(4):289-98.

PMID:1224883
Abstract

The microcirculation of 46 autoperfused heart-lung-liver-duodenum-pancreas-kidney preparations has been studied and the acid-base conditions were determined. The stability of the autoperfused organ preparation was not ensured by the "multi-organ" arrangement, moreover the combination had a detrimental effect, with reduced tissue perfusion leading to hypoxia and acidosis. This general vasomotor breakdown represented a therapeutic drug resistance, so that the organ preparation failed to solve the problem of temporary organ preservation.

摘要

对46个自体灌注心肺肝肾十二指肠胰腺标本的微循环进行了研究,并测定了酸碱状况。“多器官”组合方式并不能确保自体灌注器官标本的稳定性,而且这种组合具有有害作用,组织灌注减少会导致缺氧和酸中毒。这种普遍的血管舒缩功能衰竭表现为对治疗药物的抵抗,因此器官标本未能解决临时器官保存的问题。

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