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小猫视觉诱发电反应和视觉引导行为的发育:上丘和外侧膝状体损伤的影响。

Development of visually evoked responses and visually guided behavior in kittens: effects of superior colliculus and lateral geniculate lesions.

作者信息

Atwell C W, Lindsley D B

出版信息

Dev Psychobiol. 1975 Sep;8(5):465-78. doi: 10.1002/dev.420080511.

DOI:10.1002/dev.420080511
PMID:1225709
Abstract

The development of visually evoked responses (VER's) and visually guided behavior was studied in kittens for 3 months after unilateral lesions of the superior colliculus (SC) or lateral geniculate nucleus (LGN) made at an early age. Of 37 kittens studied, data are presented for 6 which met 3 criteria: survival to at least 90 days of age; adequate lesion size and location; and technically satisfactory VER's and behavioral observations at appropriate intervals. The SC and LGN lesions markedly reduced or eliminated different VER components in infancy, but only the effects of LGN lesions persisted to 3 months of age. Visual field behavior deficits occurred following both types of lesions, but only those following SC lesions persisted to 3 months of age. These results are interpreted in terms of the functional status of the structures mediating the VER's and behavior at the time the lesions were made.

摘要

在幼猫早期单侧损毁上丘(SC)或外侧膝状体核(LGN)后,对其视觉诱发电位(VER)和视觉引导行为的发育进行了为期3个月的研究。在研究的37只幼猫中,给出了6只符合3项标准的幼猫的数据:存活至至少90日龄;损毁大小和位置合适;在适当间隔期有技术上令人满意的VER及行为观察结果。SC和LGN损毁在幼年期显著降低或消除了不同的VER成分,但只有LGN损毁的影响持续到3月龄。两种类型的损毁后均出现视野行为缺陷,但只有SC损毁后的缺陷持续到3月龄。根据损毁发生时介导VER和行为的结构的功能状态对这些结果进行了解释。

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