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[获得性鱼鳞病作为霍奇金病的皮肤症状。副肿瘤综合征]

[Acquired ichthyosis as a cutaneous symptom of Hodgkin's disease. Paraneoplastic syndrome].

作者信息

Bartsokas S, Stratigos J, Karambali S, Kassimatis B, Kapetanakis J

出版信息

Fortschr Med. 1975 Oct 23;93(30):1493-6.

PMID:1225809
Abstract

A case-report of a patient with acquired ichthyosis is given. The symptoms of the main disease-ascites, heavy edema, cachexia and general dissolution-became manifest at the same time as the cutaneous manifestations. The histological examination of a neck lymph node showed metastases of a carcinoma of the gastrointestinal tract. The autopsy resulted in the diagnosis M. Hodgkin. The dermatosis (ichthyosis) is explained as cutaneous pareneoplastic syndrome. The pathogenesis of the disease and the possible role of A-vitaminosis resp. disturbance of vit. A metabolism in the manifestation of the cutaneous manifestations is discussed.

摘要

本文报告了一例获得性鱼鳞病患者。主要疾病的症状——腹水、重度水肿、恶病质和全身衰竭——与皮肤表现同时出现。颈部淋巴结的组织学检查显示为胃肠道癌转移。尸检诊断为霍奇金病。这种皮肤病(鱼鳞病)被解释为皮肤副肿瘤综合征。本文讨论了该病的发病机制以及维生素A缺乏症和维生素A代谢紊乱在皮肤表现中的可能作用。

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