Siziakina L P
Probl Endokrinol (Mosk). 1975 Jul-Aug;21(4):60-2.
Experiments were conducted on 30 rats; a study was made of the morphometric and quantitative enzymatico-chemical changes in the glomerular zone of the adrenal cortex in stereotaxic disturbance of the subcomissural organ; there was established a marked atrophy of the glomerular zone, a significant reduction of the diameter of the nuclei of the adrenocorticocytes and depression in these structures of the enzymatic activity of the energy metabolism. Histophysiological characteristics of the glomerular zone can be assessed as its hypofunctional condition and indicates an association between the functional activity of the subcommissural organ and the production of aldosterone.
对30只大鼠进行了实验;研究了在室管膜下器官立体定向损伤时肾上腺皮质球状带的形态计量学和定量酶化学变化;发现球状带明显萎缩,肾上腺皮质细胞的核直径显著减小,这些结构中的能量代谢酶活性降低。球状带的组织生理学特征可评估为其功能减退状态,表明室管膜下器官的功能活动与醛固酮的产生之间存在关联。