实验性心肌梗死后非梗死心肌中去甲肾上腺素的代谢
Metabolism of norepinephrine in noninfarcted heart muscle after experimental myocardial infarction.
作者信息
Mathes P, Sack D W, Gudbjarnason S
出版信息
Recent Adv Stud Cardiac Struct Metab. 1975;7:283-7.
PMID:1226441
Abstract
A marked, reversible decline in cardiac norepinephrine (NE) stores was noted after experimental myocardial infarction. Uptake and accumulation of tracer dose of dl-[7-14C]norepinephrine appeared to be unchanged as well as the rate of degradation. Despite marked variations in pool size the subcellular distribution appeared to be unchanged, and no preferential uptake into any subcellular fraction was observed.
摘要
实验性心肌梗死后，观察到心脏去甲肾上腺素（NE）储备有明显的、可逆性下降。示踪剂量的dl-[7-¹⁴C]去甲肾上腺素的摄取和蓄积以及降解速率似乎未发生改变。尽管储备池大小存在显著差异，但亚细胞分布似乎未变，且未观察到有任何亚细胞组分的优先摄取现象。
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