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1
Use of miconazole for prevention of opportunistic fungal infection during treatment of haematological malignancies.咪康唑在血液系统恶性肿瘤治疗期间预防机会性真菌感染中的应用。
Proc R Soc Med. 1977;70 Suppl 1(Suppl 1):32-4. doi: 10.1177/00359157770700S110.
2
[Systemic fungal infections in hematologic neoplasms. An autopsy study of 1,053 patients].[血液系统肿瘤中的系统性真菌感染。对1053例患者的尸检研究]
Med Klin (Munich). 1994 Jun 15;89(6):299-304.
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[Risk factors for invasive fungal infections during intensive chemotherapy of acute leukemia--retrospective study].[急性白血病强化化疗期间侵袭性真菌感染的危险因素——回顾性研究]
Acta Med Croatica. 2004;58(4):275-84.
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[Prophylaxis against mycoses in neutropenic patients].中性粒细胞减少患者的霉菌病预防
Mycoses. 1994;37 Suppl 2:70-6.
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[Prevention of mycotic infections in oncology patients with regard to the toxicity of antimycotic agents].[关于抗真菌药物毒性的肿瘤患者真菌性感染预防]
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Reduced colonization and infection with miconazole-rifampicin modified central venous catheters: a randomized controlled clinical trial.咪康唑-利福平改良中心静脉导管减少定植与感染：一项随机对照临床试验
J Antimicrob Chemother. 2004 Dec;54(6):1109-15. doi: 10.1093/jac/dkh483. Epub 2004 Nov 10.
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Prophylactic treatment with miconazole in patients highly predisposed to fungal infection. A placebo-controlled double-blind study.对极易发生真菌感染的患者进行咪康唑预防性治疗。一项安慰剂对照双盲研究。
Acta Med Scand. 1978;204(1-2):123-8. doi: 10.1111/j.0954-6820.1978.tb08410.x.
8
Intravenous and intrathecal miconazole therapy for systemic mycoses.静脉内和鞘内注射咪康唑治疗全身性真菌病。
West J Med. 1977 Jan;126(1):5-13.
9
Clinical and experimental evidence on miconazole for the treatment of systemic mycoses: a review.咪康唑治疗全身性真菌病的临床与实验证据综述
Proc R Soc Med. 1977;70 Suppl 1(Suppl 1):4-8. doi: 10.1177/00359157770700S103.
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Treatment of fungal infections with miconazole.用咪康唑治疗真菌感染。
Proc R Soc Med. 1977;70 Suppl 1(Suppl 1):40-2. doi: 10.1177/00359157770700S112.

引用本文的文献

1
Miconazole: a preliminary review of its therapeutic efficacy in systemic fungal infections.咪康唑：对其在全身性真菌感染中治疗效果的初步综述。
Drugs. 1980 Jan;19(1):7-30. doi: 10.2165/00003495-198019010-00002.

咪康唑在血液系统恶性肿瘤治疗期间预防机会性真菌感染中的应用。

Use of miconazole for prevention of opportunistic fungal infection during treatment of haematological malignancies.

作者信息

Michaux J L, Jacquemin P, Cornu G, Wauters G, Gigi J, Noel H, Turine J B, Ferrant A

机构信息

Department of Internal Medicine, St-Pierre University Hospital, Louvain, Belgium.

出版信息

Proc R Soc Med. 1977;70 Suppl 1(Suppl 1):32-4. doi: 10.1177/00359157770700S110.

DOI:10.1177/00359157770700S110
PMID:122645
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1542853/
Abstract

It appears that miconazole is highly effective in reducing the incidence of systemic mycosis in patients suffering from malignant haemopathy and bone marrow failure. Three clinical infections (one stomatitis and two septicaemias due to candida) were easily cured. Autopsy findings never disclosed mycosis as the cause of death. The drug was completely atoxic and seems to offer major help in the treatment of malignant blood disease.

摘要

咪康唑似乎对降低患有恶性血液病和骨髓衰竭患者的系统性真菌病发病率非常有效。三例临床感染（一例念珠菌性口腔炎和两例念珠菌性败血症）很容易治愈。尸检结果从未显示真菌病是死因。该药物完全无毒，似乎在恶性血液病的治疗中能提供很大帮助。