Gamberale F, Annwall G, Hultengren M
Scand J Work Environ Health. 1975 Jun;1(2):95-103. doi: 10.5271/sjweh.2851.
The effect of the solvent methylene chloride on psychological functions such as reaction time, short-term memory, and numerical ability was studied in 14 healthy male subjects. Each subject was tested repeatedly during exposure to 870, 1,740, 2,600, and 3,470 mg/m3 of methylene choride in inspiratory air and during control conditions. Samples of sub ject alveolar air were taken every third minute during the experiments. No statistically significant impairement in the performance of examined functions could be observed during exposure to methylene choride as compared to control conditions. Inexposure to the highest concentration a greater irregularity of response was obtained for subject reaction time than under control conditions.
在14名健康男性受试者中研究了溶剂二氯甲烷对反应时间、短期记忆和数字能力等心理功能的影响。在吸入空气中二氯甲烷浓度分别为870、1740、2600和3470mg/m³的暴露期间以及对照条件下，对每名受试者进行了重复测试。实验过程中每隔三分钟采集一次受试者肺泡气样本。与对照条件相比，在二氯甲烷暴露期间未观察到所检测功能表现有统计学意义的损害。在暴露于最高浓度时，受试者反应时间的反应比对照条件下更不规则。
