Daculsi G, Kerebel B
Centre de Recherche, Faculté de Chirurgie Dentaire, Nantes, France.
J Biol Buccale. 1977 Sep;5(3):203-18.
High resolution electron microscope techniques now make it possible to study the mineralization of calcified tissues at the crystal structure level. Dislocations play an important part in the course of crystal maturation and modifications. At least two origins of dislocations are known. The first is due to phenomena related to the incorporation of fluoride ions into the lattice. The second is due to mechanical stresses occurring between crystals during their maturation. Dislocations are the starting-points of acid dissolution which proceeds along dislocation-lines, sometimes inducing a splitting of the crystals. In the present study, dislocations have been visualized, either isolated in the crystal core and perhaps the two-dimensional surface representation of a screw-shaped dislocation, or forming nets of dislocations producing a spiral staircase on the sides faces of the crystals. There is evidence of a maturation cycle of the crystals, which may grow, split, coalesce or dissolve; liberated elements and small crystal fragments may allow development of near-by crystals. This remodelling explains the existence of a standard size as well as the perfect fitting of the crystals. These morphological data involve physico-chemical properties of biological apatites.
高分辨率电子显微镜技术现在使在晶体结构水平上研究钙化组织的矿化成为可能。位错在晶体成熟和改性过程中起着重要作用。已知位错至少有两个起源。第一个起源是由于与氟离子掺入晶格相关的现象。第二个起源是由于晶体成熟过程中晶体之间产生的机械应力。位错是沿着位错线进行的酸溶解的起点，有时会导致晶体分裂。在本研究中，位错已被可视化，要么孤立于晶体核心，可能是螺旋形位错的二维表面表现形式，要么形成位错网络，在晶体侧面产生螺旋楼梯状。有证据表明晶体存在成熟周期，晶体可能生长、分裂、合并或溶解；释放的元素和小晶体碎片可能促进附近晶体的发育。这种重塑解释了标准尺寸的存在以及晶体的完美契合。这些形态学数据涉及生物磷灰石的物理化学性质。
