Brown Tricia J, McCrary Monica, Tyring Stephen K
Department of Dermatology, Microbiology/Immunology and Internal Medicine, University of Texas Medical Branch, Galveston 77555, USA.
J Am Acad Dermatol. 2002 Oct;47(4):581-99. doi: 10.1067/mjd.2002.121033.
The current arsenal of antiviral agents available to the practitioner is expanding rapidly, such that by the time this article goes to press, new drugs may have already been added. Although the majority of approved drugs have been developed for use in only a few viral infections (eg, HIV, herpesviruses, and papillomavirus), discoveries made in the development of these drugs may lead to antiviral agents effective against other viruses. In addition, new uses for the currently available drugs are under evaluation. This review of antiviral agents discusses the treatments available for viral infections such as herpes simplex virus, varicella zoster virus, cytomegalovirus, human papillomavirus, chronic viral hepatitis, and others.
目前临床医生可用的抗病毒药物库正在迅速扩大,以至于在本文付梓之时,可能已经有新药被添加进来。尽管大多数已获批的药物仅针对少数几种病毒感染研发(如艾滋病毒、疱疹病毒和乳头瘤病毒),但这些药物研发过程中的发现可能会催生对其他病毒有效的抗病毒药物。此外,目前可用药物的新用途也在评估之中。这篇抗病毒药物综述讨论了可用于治疗单纯疱疹病毒、水痘带状疱疹病毒、巨细胞病毒、人乳头瘤病毒、慢性病毒性肝炎等病毒感染的治疗方法。