Talas M, Gazárak F, Stehliková J, Lubuský D, Fingerová H
Zentralbl Gynakol. 1975;97(25):1580-7.
Using the radioimmunological method, FSH and LH levels were determined in women immediately after surgical castration and after an elapse of 18 months to two years. A twofold increase in FSH was found already two days after castration, while an increase in LH only after six days. Increased FSH and LH levels were observed as late as after two years when upon the administraion of estrogens and androgens, the feed-back mechanism of the pituitary still plays a role. In women with pronounced menopausal disturbances the FSH and LH levels were followed up after the application of Folivirin and Agofollin-Depot over a period of two weeks. There was a constant decrease in FSH of all women immediately after the injection, while the responses in LH were subject to variation, the decreased LH levels being found in all the women only towards the end of the second week. Folivirin was found more suitable for mastering the menopausal disturbances.
采用放射免疫法,对女性在手术去势后即刻以及经过18个月至两年的时间后测定促卵泡激素(FSH)和促黄体生成素(LH)水平。去势后两天就发现FSH增加了两倍,而LH在六天后才增加。直到两年后,当给予雌激素和雄激素时,垂体的反馈机制仍起作用,此时仍观察到FSH和LH水平升高。对于有明显绝经紊乱的女性,在应用Folivirin和长效促卵泡素(Agofollin-Depot)两周期间对FSH和LH水平进行跟踪监测。所有女性在注射后即刻FSH持续下降,而LH的反应存在差异,所有女性仅在第二周快结束时LH水平才下降。发现Folivirin更适合于控制绝经紊乱。