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[豚鼠衣原体实验性感染。1. 病理形态学研究]

[Experimental infection of guinea pigs with Chlamydia. 1. Pathomorphological studies].

作者信息

Ilchmann G, Baumann G, Gottwald G

出版信息

Arch Exp Veterinarmed. 1975 Dec;29(6):869-78.

PMID:1227428
Abstract

The changes that occurred following nasal instillation of a bovine strain of Chlamydia psittaci were characterized by hypertrophy and proliferation of epithelial cells and exudates containing polymorphonuclear leukocytes, with acute bronchopneumonia and less intense inflammatory reactions in nasal and tracheal mucosa, spleen and pulmonary lymph nodes. The intestines, liver, kidney and brain were scarcely affected. There was little prospect of complete recovery from the clinically mild, or even subclinical, pneumonia within the period of observation since the causal agent was present continuously from the 12th hour to the 91st day after infection.

摘要

鼻内接种一株牛源鹦鹉热衣原体后所发生的变化,其特征为上皮细胞肥大和增生,以及含有多形核白细胞的渗出物,伴有急性支气管肺炎,且鼻和气管黏膜、脾脏及肺淋巴结的炎症反应较轻。肠道、肝脏、肾脏和大脑几乎未受影响。由于致病因子在感染后第12小时至第91天持续存在,因此在观察期内,从临床症状轻微甚至亚临床的肺炎中完全康复的可能性很小。

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