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日本鹌鹑对溃疡性肠炎易感性的遗传差异。

Genetic differences in susceptibility to ulcerative enteritis in Japanese quail.

作者信息

Collins W M, Hardiman J W, Urban W E, Corbett A C

出版信息

Poult Sci. 1975 Nov;54(6):2051-4. doi: 10.3382/ps.0542051.

DOI:10.3382/ps.0542051
PMID:1228728
Abstract

Six lines of Japanese quail were derived from a single foundation population. Four of the lines were selected on the basis of family mean three week body weight, two were unselected and all lines were randomly mated. Quail were housed in wire batteries during the brooding, rearing and laying periods. During the brooding period, hover temperature and floor space per chick were similar from line to line. For the rearing and laying periods, floor space per chick was approximately the same from line to line. During an outbreak of ulcerative enteritis (diagnosed on the basis of gross and histopathology) in generation 31 and again in generation 34, mortality ranged from zero for males of one control line to approximately 50 percent for females of one selected line. Analysis of variance showed that incidence of mortality differed significantly among lines and between sexes. Mortality was generally higher in selected than in control lines and in females than in males. It is suggested that susceptibility to ulcerative enteritis in quail may be a polygenically inherited trait and that the breeding which accompanied selection for body size may have made some loci homozygous for susceptibility alleles.

摘要

六系日本鹌鹑源自单一基础种群。其中四系根据家系平均三周龄体重进行选育,两系未进行选育,所有品系均随机交配。在育雏、育成和产蛋期,鹌鹑饲养于铁丝笼中。育雏期,各品系每只雏鹑的育雏温度和占地面积相似。育成期和产蛋期,各品系每只雏鹑的占地面积大致相同。在第31代和第34代爆发溃疡性肠炎(根据大体病理和组织病理学诊断)期间,死亡率从一个对照系雄性的零至一个选育系雌性的约50%不等。方差分析表明,品系间和性别间的死亡率发生率存在显著差异。一般来说,选育系的死亡率高于对照系,雌性的死亡率高于雄性。有人认为,鹌鹑对溃疡性肠炎的易感性可能是一种多基因遗传性状,并且伴随体型选择的育种可能使一些位点对易感等位基因纯合。

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