Fievez M, Koerperich G, Dulieu J
Ann Anat Pathol (Paris). 1975 Aug-Oct;20(4):357-66.
Renal arteries of a 29-year-old hypertensive woman are described typical of fibro muscular dysplasia. Segmental stenoses of femoral, humeral and carotid arteries are associated. The histological study of one renal artery discloses a sub-adventitial fibrosis; besides there are pictures which are very close to those found during chronic intoxication with ergotamine tartrate. Patient history confirms this intoxication. Discontinuation of the ergotamine intoxication and administration of vaso-dilating substances are associated with a dramatic subjective and objective improvement of renal and peripheral arterial signs. The reversibility of the symptoms constitutes a serious clinical proof of the hypothesis of Bercquist and coll. (1971): that a prolonged arterial spasm could represent a promoting factor of arterial fibro-muscular dysplasias.
一名29岁高血压女性的肾动脉表现出典型的纤维肌发育不良。同时伴有股动脉、肱动脉和颈动脉的节段性狭窄。对一条肾动脉的组织学研究显示外膜下纤维化;此外,还有一些图像与酒石酸麦角胺慢性中毒时发现的图像非常相似。患者病史证实了这种中毒情况。停止麦角胺中毒并给予血管扩张剂后,肾脏和外周动脉症状在主观和客观上都有显著改善。症状的可逆性构成了Bercquist等人(1971年)假说的一个重要临床证据:即长期的动脉痉挛可能是动脉纤维肌发育不良的一个促发因素。