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Acute changes of the Na-K-ATPase-activity in plasmamembranes of the isolated, cell-free perfused rat kidney.

作者信息

Franke H, Mályusz M, Weiss C, Unsicker K

出版信息

Pflugers Arch. 1975;353(2):97-106. doi: 10.1007/BF00599871.

DOI:10.1007/BF00599871
PMID:123058
Abstract

The Na-K-ATPase-activity of the isolated, cell-free perfused rat kidney was investigated. Na-load and perfusion rate could be varied independently. The ATPase-assay was carried out on plasmamembranes (700-1200 g fraction) isolated and purified after 60 min perfusion. Both the specific Na-K-ATPase-activity and the fractional Na-reabsorption showed an indirect correlation with the Na-load as well as with the perfusion rate. The Na-K-ATPase-activity of plasmamembranes obtained from the isolated kidney at physiological Na-load fits well to control values prepared from unperfused control kidneys. The present data are in accord with the results of earlier micropuncture experiments, where acute saline loading diminished the rate of Na-absorption.

摘要

相似文献

1
Acute changes of the Na-K-ATPase-activity in plasmamembranes of the isolated, cell-free perfused rat kidney.
Pflugers Arch. 1975;353(2):97-106. doi: 10.1007/BF00599871.
2
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引用本文的文献

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本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
The sodium-stimulated adenosine-triphosphatase activity and other properties of cerebral microsomal fractions and subfractions.脑微粒体组分及亚组分的钠刺激三磷酸腺苷酶活性和其他特性。
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[Sodium and water reabsorption in different parts of the nephron in rats with experimental hypertension].[实验性高血压大鼠肾单位不同部位的钠和水重吸收]
Pflugers Arch. 1968;304(4):322-35. doi: 10.1007/BF00587708.
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On the glomerular tubular balance in the rat kidney.关于大鼠肾脏的肾小球肾小管平衡
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Improved net sodium transport of the isolated rat kidney.
Z Gesamte Exp Med Einschl Exp Chir. 1971;156(4):268-82. doi: 10.1007/BF02045828.
7
Measurements of the critical PO2 of renal mitochondria.
Pflugers Arch. 1971;323(3):250-7. doi: 10.1007/BF00586387.
8
Induction of Na K ATPase in the proximal and distal convolution of the rat nephron after uninephrectomy.单侧肾切除术后大鼠肾单位近曲小管和远曲小管中钠钾ATP酶的诱导作用。
Pflugers Arch. 1974 Jan 16;346(1):39-48. doi: 10.1007/BF00592649.
9
The role of aldosterone in the regulation of (Na + + K + )-ATPase in rat kidney.醛固酮在大鼠肾脏中对（钠+ +钾+）-ATP酶的调节作用。
J Steroid Biochem. 1972 Feb;3(2):181-91. doi: 10.1016/0022-4731(72)90049-0.
10
Effect of extracellular volume expansion on renal cortical and medullary Na + -K + -ATPase.
Pflugers Arch. 1971;330(2):136-48. doi: 10.1007/BF00643030.