Marconi G P, Arretoli G
Riv Patol Nerv Ment. 1975 Jul-Aug;96(4):239-51.
A twenty year old man affected by Guillain-Barré's radiculopolyneuritis with tetraparesis had high protein and only few cells in the C.S.F., with no cranial nerve involvement or respiratory difficulty. He had high arterial pressure (both diastolic and systolic) for about three months accompanied by episodes of tachycardia and hyperhydrosis. Investigations of renal functionas well as catecholamine and vanil-mandelic acid urinary excretion were normal. Tilting test and carotid sinus reflex were normal. The patient recovered almost completely eight months after the onset of his illness. The presence of arterial hypertension in the Guillain-Barré's syndrome has been rarely reported with no respiratory involvement; however this condition may be less rare than suspected. The pathogenesis of this complication is not easy to explain. According to the authors this condition may be due, in cases, to impairment of the sympathetic system mostly at peripheral level. In some cases of Guillain-Barré's syndrome renal involvement of immunopathological origin might be the cause of hypertension. The authors emphasize the importance of a correct evaluation of symptoms in the prognosis and in the choice of therapy.
一名20岁患有格林-巴利神经根多神经炎并伴有四肢轻瘫的男子,其脑脊液中蛋白质含量高而细胞数量少,无颅神经受累或呼吸困难。他的动脉血压(舒张压和收缩压)升高约三个月,伴有心动过速和多汗发作。肾功能以及儿茶酚胺和香草扁桃酸的尿排泄检查均正常。倾斜试验和颈动脉窦反射正常。患者在发病八个月后几乎完全康复。格林-巴利综合征中出现动脉高血压且无呼吸受累的情况很少见报道;然而,这种情况可能比怀疑的更为常见。这种并发症的发病机制不易解释。据作者称,这种情况在某些病例中可能是由于交感神经系统主要在外周水平受损所致。在一些格林-巴利综合征病例中,免疫病理起源的肾脏受累可能是高血压的原因。作者强调正确评估症状在预后和治疗选择中的重要性。