Goulon M, Nouailhat F, Babinet P, Grosbuis S, Barois A, Raphael J C, Gajdos P
Rev Neurol (Paris). 1975 Feb;131(2):95-119.
In this research involving 172 cases of acute primary polyradiculoneuritis, the authors draw attention to the frequency and seriousness of the autonomic disorders, notably circulatory disorders (arterial hypertension, bradycardia), water retention, disorders in glucose metabolism. They have found a close correlation between the development of arterial hypertension and levels of VMA and the cathecholamines and between the appearance of hyperglycaemia and the level of urinary 17 OH. Free water clearance is often negative and becomes positive as the paralytic syndrome improves. The biological picture is identical with that brought about by inappropriate secretion of HAD. From the therapeutic point of view, caution is advised in using certain procedures and in prescribing certain drugs.
在这项涉及172例急性原发性多发性神经根神经炎的研究中，作者提请注意自主神经功能紊乱的发生率和严重性，尤其是循环系统紊乱（动脉高血压、心动过缓）、水潴留、糖代谢紊乱。他们发现动脉高血压的发生与香草扁桃酸（VMA）和儿茶酚胺水平之间，以及高血糖的出现与尿17-羟皮质类固醇水平之间存在密切相关性。自由水清除率常为负值，随着麻痹综合征的改善而转为正值。生物学表现与抗利尿激素分泌不当所引起的情况相同。从治疗角度来看，建议在采用某些治疗措施和开某些药物时要谨慎。
