Das V K, Swarup K
Arch Anat Microsc Morphol Exp. 1975;64(3):261-72.
Thirty two specimens of Rana tigrina were divided into four equal groups : group I = controls; group II = injected with Vitamin D2 and placed in a 0.8% aqueous solution of CaCl2; group III = injected with Vitamin D2 and kept in tap water; group IV = placed only in a 0.8% CaCl2 solution. The experimental specimens exhibited varying degrees of hyperactivity of their ultimobranchial gland. Specimens from all the groups were X-rayed. The experimental ones showed different intensity of calcium deposit in their paravertebral lime sacs. The results indicate that prolonged challenge of high calcium induces hyperactivity of the ultimobranchial gland to produce larger quantity of calcitonin, to counteract the experimental hypercalcemia.
32只虎纹蛙标本被分成四组,每组数量相等:第一组为对照组;第二组注射维生素D2并置于0.8%的氯化钙水溶液中;第三组注射维生素D2并置于自来水中;第四组仅置于0.8%的氯化钙溶液中。实验标本的 ultimobranchial 腺呈现出不同程度的活动亢进。对所有组的标本进行了X光检查。实验组在其椎旁石灰囊中显示出不同强度的钙沉积。结果表明,长期高钙刺激会诱导 ultimobranchial 腺活动亢进,以产生更多的降钙素,从而抵消实验性高钙血症。