Stoeckel H
Prakt Anaesth. 1975 Dec;10(6):317-24.
The effects of intravenous and general anaesthesia on the cerebral circulation and metabolism are reviewed. The various anaesthetic agents differ both quantitatively and qualitatively in their action on the brain. The pathophysiology of raised intracranial pressure is discussed and the risks involved in the use of certain anaesthetic agents in cases of reduced intracranial compliance are emphasized. Details are given of the safe limits for induced changes in pCO2 and arterial pressure.
本文综述了静脉麻醉和全身麻醉对脑循环及代谢的影响。各种麻醉剂对大脑的作用在数量和质量上均有所不同。文中讨论了颅内压升高的病理生理学,并强调了在颅内顺应性降低的情况下使用某些麻醉剂所涉及的风险。文中还给出了诱导性pCO2和动脉压变化的安全限度的详细信息。