Immune reaction in the gastric mucosa: passive mucosal anaphylaxis and experimental ulcer.

Immune reaction in the gastric mucosa using purified antigen-antibody system was investigated. Applying the technique of PCA on the gastric mucosa of dog, interesting phenomena named "Passive Mucosal Anaphylaxis (PMA) was obtained. The reaction could be produced even by the orally administered antigen. By the direct injection of soluble immune complex into the gastric mucosa, production of experimental ulcer was observed, in which parietal cells were relatively resistent to the immune tissue damage.