皮肤羟类固醇脱氢酶与大鼠毛发周期
Cutaneous hydroxystereoid dehydrogenases and rat-hair cycle.
作者信息
Crovato F, Bertamino R, Moretti G
出版信息
Arch Dermatol Forsch. 1975;251(4):325-8.
PMID:123437
Abstract
The histochemical activity pattern of a number of hydroxysteroid dehydrogenases was studied during a provoked hair cycle in the rat skin. The intensity of reaction was high with dehydroepiandrosterone, estradiol, androsterone and pregnenolone, and none with 11-beta-hydroxyprogesterone, testosterone, dihydrotestosterone, 17-alpha-hydroxypregnenolone and 17-alpha-hydroxyprogesterone. Reactivity also varied with the hair cycle. The reactive sit-s were the acini of sebaceous glands and the hair sheaths.
摘要
在大鼠皮肤诱发毛发生长周期过程中，对多种羟基类固醇脱氢酶的组织化学活性模式进行了研究。脱氢表雄酮、雌二醇、雄酮和孕烯醇酮的反应强度较高，而11-β-羟基孕酮、睾酮、双氢睾酮、17-α-羟基孕烯醇酮和17-α-羟基孕酮则无反应。反应性也随毛发生长周期而变化。反应部位是皮脂腺腺泡和毛鞘。
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