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皮肤羟类固醇脱氢酶与大鼠毛发周期

Cutaneous hydroxystereoid dehydrogenases and rat-hair cycle.

作者信息

Crovato F, Bertamino R, Moretti G

出版信息

Arch Dermatol Forsch. 1975;251(4):325-8.

PMID:123437
Abstract

The histochemical activity pattern of a number of hydroxysteroid dehydrogenases was studied during a provoked hair cycle in the rat skin. The intensity of reaction was high with dehydroepiandrosterone, estradiol, androsterone and pregnenolone, and none with 11-beta-hydroxyprogesterone, testosterone, dihydrotestosterone, 17-alpha-hydroxypregnenolone and 17-alpha-hydroxyprogesterone. Reactivity also varied with the hair cycle. The reactive sit-s were the acini of sebaceous glands and the hair sheaths.

摘要

在大鼠皮肤诱发毛发生长周期过程中,对多种羟基类固醇脱氢酶的组织化学活性模式进行了研究。脱氢表雄酮、雌二醇、雄酮和孕烯醇酮的反应强度较高,而11-β-羟基孕酮、睾酮、双氢睾酮、17-α-羟基孕烯醇酮和17-α-羟基孕酮则无反应。反应性也随毛发生长周期而变化。反应部位是皮脂腺腺泡和毛鞘。

相似文献

1
Cutaneous hydroxystereoid dehydrogenases and rat-hair cycle.皮肤羟类固醇脱氢酶与大鼠毛发周期
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2
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The presence of hydroxysteroid dehydrogenases in mammalian sebaceous structures.
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引用本文的文献

1
The role of neprilysin in regulating the hair cycle.脑啡肽酶在调控毛发周期中的作用。
PLoS One. 2013;8(2):e55947. doi: 10.1371/journal.pone.0055947. Epub 2013 Feb 13.

本文引用的文献

1
3-BETA-HYDROXYSTEROID DEHYDROGENASE IN THE ADRENAL GLAND AND PLACENTA.
J Endocrinol. 1965 Feb;31:227-33. doi: 10.1677/joe.0.0310227.
2
Histochemical distribution of hydroxysteroid dehydrogenases in human skin.
Br J Dermatol. 1965 Dec;77(12):610-6. doi: 10.1111/j.1365-2133.1965.tb14591.x.
3
17- -Hydroxy-steroid-dehydrogenases in hair follicles of normal and bald scalp: a histochemical study.
J Invest Dermatol. 1973 Mar;60(3):126-33. doi: 10.1111/1523-1747.ep12682032.
4
Hydroxysteroid dehydrogenases in normal and abnormal human testes.正常和异常人类睾丸中的羟基类固醇脱氢酶
J Endocrinol. 1966 Jul;35(3):239-48. doi: 10.1677/joe.0.0350239.
5
Histochemical utilization of 3-alpha-, 6-beta-, 12-alpha-, 16-alpha-, 16-beta-, 17-alpha-, 21- and 24 hydroxysteroids.3-α-、6-β-、12-α-、16-α-、16-β-、17-α-、21-和24-羟基类固醇的组织化学应用
J Endocrinol. 1966 Jan;34(1):1-12. doi: 10.1677/joe.0.0340001.
6
Hydroxysteroid dehydrogenase activity in human skin. I. Histochemical techniques for the demonstration of 3-beta-hydroxysteroid dehydrogenase, and a method for the semiquantitation of its activity.
Br J Dermatol. 1968 Sep;80(9):594-600. doi: 10.1111/j.1365-2133.1968.tb12358.x.
7
Dehydroepiandrosterone- and glucose-6-phosphate-dehydrogenases in the hair cycle of the rat.大鼠毛发周期中的脱氢表雄酮和葡萄糖-6-磷酸脱氢酶
Arch Dermatol Forsch. 1970;240(1):55-60. doi: 10.1007/BF01036167.
8
The presence of hydroxysteroid dehydrogenases in mammalian sebaceous structures.
Br J Dermatol. 1970 Aug;83(2):291-5. doi: 10.1111/j.1365-2133.1970.tb15702.x.