心率对麻醉犬左心室肌肉相性和局部血流的可变影响。
Variable effects of heart rate on phasic and regional left ventricular muscle blood flow in anaesthetized dogs.
作者信息
Buckberg G D, Fixler D E, Archie J P, Henney R P, Hoffman J I
出版信息
Cardiovasc Res. 1975 Jan;9(1):1-11. doi: 10.1093/cvr/9.1.1.
PMID:123481
Abstract
Tachycardia to 240 beats/min in anaesthetized dogs increases coronary blood flow while flow in the left ventricular wall remains homogeneous. An arteriovenous fistula causes subendocardial ischaemia at 120 beats/min but pacing to 180 to 210 beats/min increases subendocardial blood flow by increasing diastolic coronary driving pressure per minute.
摘要
麻醉犬的心率增快至240次/分钟时，冠状动脉血流量增加，而左心室壁内血流仍保持均匀。动静脉瘘在心率为120次/分钟时可导致心内膜下缺血，但将心率起搏至180至210次/分钟时，通过增加每分钟舒张期冠状动脉驱动压可增加心内膜下血流量。
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