NZF-2b是小鼠NZF-2/MyT1的一种新的主要形式，在分化的神经元中表达，尤其是在新生成的神经元中表达水平更高。

NZF-2b is a novel predominant form of mouse NZF-2/MyT1, expressed in differentiated neurons especially at higher levels in newly generated ones.

作者信息

Matsushita Fumio, Kameyama Toshiki, Marunouchi Tohru

机构信息

Division of Cell Biology, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi 470-1192, Japan.

出版信息

Mech Dev. 2002 Oct;118(1-2):209-13. doi: 10.1016/s0925-4773(02)00250-2.

DOI:10.1016/s0925-4773(02)00250-2

PMID:12351189

Abstract

NZF-2 (MyT1) is a member of C2HC-type zinc finger transcription factors. A novel form of mouse NZF-2 has been isolated. This novel form, NZF-2b, has an additional C2HC-type zinc finger motif. The expression levels of NZF-2b are by far the more predominant than those of the already known form of NZF-2. In embryonic mouse nervous system, the expression of NZF-2b starts as early as at 9.5 days post-coitum (dpc) in newly differentiated neurons in the central nervous system (CNS) and the peripheral nervous system (PNS).

摘要

NZF-2（MyT1）是C2HC型锌指转录因子家族的一员。一种新型的小鼠NZF-2已被分离出来。这种新型形式，即NZF-2b，具有一个额外的C2HC型锌指基序。到目前为止，NZF-2b的表达水平比已知形式的NZF-2更为显著。在胚胎小鼠神经系统中，NZF-2b早在妊娠9.5天（dpc）时就在中枢神经系统（CNS）和外周神经系统（PNS）新分化的神经元中开始表达。