Scedosporium apiospermum in chronic granulomatous disease treated with an HLA matched bone marrow transplant.
作者信息
Gompels M M, Bethune C A, Jackson G, Spickett G P
机构信息
Department of Immunology, Southmead Hospital, Bristol, BS10 5NB, UK Department of Immunology, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK.
出版信息
J Clin Pathol. 2002 Oct;55(10):784-6. doi: 10.1136/jcp.55.10.784.
Abstract
A patient with chronic granulomatous disease who was being treated with steroids was diagnosed with a soft tissue Scedosporium apiospermum infection. Despite extensive treatment with antifungals progression to involve solid tissue (bone) occurred. Treatment required an HLA matched bone marrow transplant, which led to complete clearance of the fungal infection, although the patient subsequently died.
摘要
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