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泌尿系统的伪阿利什霉感染及治疗选择与文献病例综述

Scedosporium apiospermum infection of the urinary system with a review of treatment options and cases in the literature.

作者信息

Benamu Esther, Yu Alexander Tin-Han, Xie Lijia, Fernandez-Pol Sebastian, Liu Anne Y, Ho Dora Y

机构信息

Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA, USA.

Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.

出版信息

Transpl Infect Dis. 2018 Feb;20(1). doi: 10.1111/tid.12804. Epub 2017 Dec 21.

DOI:10.1111/tid.12804
PMID:29111602
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5871223/
Abstract

Infection with Scedosporium species is associated with a significant morbidity and mortality and is becoming increasingly common, especially in immunocompromised patients. We describe the presentation and successful management of an immunocompromised patient with Scedosporium apiospermum infection of the upper urinary tract system, a rare disease manifestation. The current literature on urinary tract scedosporiosis is further reviewed with emphasis on treatment options and limitations of current antifungal therapy.

摘要

枝孢霉属真菌感染与显著的发病率和死亡率相关,且日益常见,尤其是在免疫功能低下的患者中。我们描述了一名免疫功能低下患者上尿路系统感染裴氏瓶霉的临床表现及成功治疗过程,这是一种罕见的疾病表现形式。本文进一步回顾了目前关于尿路枝孢霉病的文献,重点关注治疗选择及当前抗真菌治疗的局限性。

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Scedosporium apiospermum infections and the role of combination antifungal therapy and GM-CSF: A case report and review of the literature.尖端赛多孢菌感染以及联合抗真菌治疗和粒细胞巨噬细胞集落刺激因子的作用:一例病例报告及文献综述
Med Mycol Case Rep. 2016 Apr 26;11:40-3. doi: 10.1016/j.mmcr.2016.04.005. eCollection 2016 Mar.
2
Clinical and morphologic findings in disseminated Scedosporium apiospermum infections in immunocompromised patients.免疫功能低下患者播散性阿皮尤斯德氏霉感染的临床和形态学表现
Proc (Bayl Univ Med Cent). 2014 Jul;27(3):253-6. doi: 10.1080/08998280.2014.11929129.
3
Tissue penetration of antifungal agents.
抗真菌药物的组织穿透性。
Clin Microbiol Rev. 2014 Jan;27(1):68-88. doi: 10.1128/CMR.00046-13.
4
Utility of DNA sequencing for direct identification of invasive fungi from fresh and formalin-fixed specimens.DNA 测序在直接鉴定新鲜和福尔马林固定标本中的侵袭性真菌中的应用。
Am J Clin Pathol. 2013 Aug;140(2):203-8. doi: 10.1309/AJCPNSU2SDZD9WPW.
5
Combination Antifungal Therapy in the Treatment of Scedosporium apiospermum Central Nervous System Infections.联合抗真菌治疗在治疗尖端赛多孢中枢神经系统感染中的应用
Case Rep Infect Dis. 2013;2013:589490. doi: 10.1155/2013/589490. Epub 2013 Apr 29.
6
Invasive non-Aspergillus mold infections in transplant recipients, United States, 2001-2006.2001-2006 年美国移植受者中侵袭性非曲霉属霉菌感染。
Emerg Infect Dis. 2011 Oct;17(10):1855-64. doi: 10.3201/eid1710.110087.
7
Candida urinary tract infections--treatment.念珠菌性尿路感染——治疗。
Clin Infect Dis. 2011 May;52 Suppl 6:S457-66. doi: 10.1093/cid/cir112.
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In vitro and in vivo studies to characterize the clearance mechanism and potential cytochrome P450 interactions of anidulafungin.旨在表征阿尼芬净清除机制及潜在细胞色素P450相互作用的体外和体内研究。
Antimicrob Agents Chemother. 2009 Mar;53(3):1149-56. doi: 10.1128/AAC.01279-08. Epub 2008 Nov 24.
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Treatment of scedosporiosis with voriconazole: clinical experience with 107 patients.伏立康唑治疗足放线病菌病:107例患者的临床经验
Antimicrob Agents Chemother. 2008 May;52(5):1743-50. doi: 10.1128/AAC.01388-07. Epub 2008 Jan 22.
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