Bendeck Sandra E, Nino-Murcia Matilde, Berry Gerald J, Jeffrey R Brooke
Department of Radiology, Stanford University Medical Center, 300 Pasteur Dr, Rm H1307, Stanford, CA 94305, USA.
Radiology. 2002 Oct;225(1):131-6. doi: 10.1148/radiol.2251011780.
To determine which patients suspected of having acute appendicitis benefit from preoperative imaging.
The medical records of 462 consecutive patients who underwent appendectomy for clinically suspected acute appendicitis and underwent preoperative evaluation at our institution were retrospectively reviewed. Patients were divided into four groups: women (n = 166), girls (n = 46), men (n = 178), and boys (n = 72). Preoperative computed tomography (CT) or ultrasonography (US), requested by the referring clinician, was performed in 313 of the 462 patients. Unnecessary, or negative, appendectomy and perforation rates were calculated for each group for preoperative evaluation with CT, with US, and with neither CT nor US. In addition, the sensitivity and positive predictive value of CT and US were calculated for diagnosing appendicitis.
In women, the negative appendectomy rate was significantly lower for those who underwent preoperative CT (7% [six of 85 patients], P =.005) or US (8% [four of 49 patients], P =.019), as compared with 28% [nine of 32 patients] for those who underwent no preoperative imaging (P >.35 for all groups). The negative appendectomy rates for girls, men, and boys were not significantly affected by preoperative imaging. The sensitivity of CT and US for diagnosing acute appendicitis exceeded 93% and 77%, respectively, in all groups. The positive predictive values for both CT and US were greater than 92% in all groups.
Women suspected of having appendicitis benefit the most from preoperative CT or US, with a statistically significantly lower negative appendectomy rate than women who undergo no preoperative imaging. Therefore, we propose that preoperative imaging be considered part of the routine evaluation of women suspected of having acute appendicitis.
确定哪些疑似急性阑尾炎的患者能从术前影像学检查中获益。
回顾性分析我院462例因临床怀疑急性阑尾炎而行阑尾切除术且接受术前评估的连续患者的病历。患者分为四组:女性(n = 166)、女孩(n = 46)、男性(n = 178)和男孩(n = 72)。462例患者中有313例应转诊医生要求进行了术前计算机断层扫描(CT)或超声检查(US)。计算了每组患者在进行CT术前评估、US术前评估以及未进行CT和US术前评估时的不必要阑尾切除术(阴性阑尾切除术)和穿孔率。此外,还计算了CT和US诊断阑尾炎的敏感性和阳性预测值。
在女性患者中,与未进行术前影像学检查的患者(28% [32例中的9例])相比,接受术前CT检查(7% [85例中的6例],P =.005)或US检查(8% [49例中的4例],P =.019)的患者阴性阑尾切除术率显著降低(所有组P>.35)。术前影像学检查对女孩、男性和男孩的阴性阑尾切除术率没有显著影响。在所有组中,CT和US诊断急性阑尾炎的敏感性分别超过93%和77%。在所有组中,CT和US的阳性预测值均大于92%。
疑似阑尾炎的女性患者从术前CT或US检查中获益最大,其阴性阑尾切除术率在统计学上显著低于未进行术前影像学检查的女性患者。因此,我们建议将术前影像学检查作为疑似急性阑尾炎女性患者常规评估的一部分。