Franco-Paredes Carlos, Martin Kelly
Department of Medicine, Emory University School of Medicine, Atlanta, GA 30303, USA.
South Med J. 2002 Sep;95(9):1101-2.
Rosai-Dorfman disease is an idiopathic histiocytic proliferative disorder characterized by sinus histiocytosis and massive lymphadenopathy. Extranodal involvement has also been reported. We report the case of a 57-year-old woman presenting with seizures, focal motor deficits, and leptomeningeal enhancement on magnetic resonance imaging. Meningeal biopsy revealed Rosai-Dorfman disease. Sinus histiocytosis may mimic meningeal disease, and Rosai-Dorfman disease should be considered in the differential diagnosis of dural-based masses with diffuse leptomeningeal enhancement.
罗萨伊-多夫曼病是一种特发性组织细胞增生性疾病，其特征为窦组织细胞增生和巨大淋巴结病。也有结外受累的报道。我们报告一例57岁女性，出现癫痫发作、局灶性运动功能缺损，磁共振成像显示软脑膜强化。脑膜活检显示为罗萨伊-多夫曼病。窦组织细胞增生可能酷似脑膜疾病，在鉴别诊断伴有弥漫性软脑膜强化的硬脑膜肿块时应考虑罗萨伊-多夫曼病。
