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因骨密度检测而接受检查的人群中,通过胸腰椎侧位X线吸收法检测椎体压缩性骨折畸形的患病率。

Prevalence of vertebral compression fracture deformity by X-ray absorptiometry of lateral thoracic and lumbar spines in a population referred for bone densitometry.

作者信息

Schousboe John T, DeBold C Rowan, Bowles Carolyn, Glickstein Scott, Rubino Ranelle K

机构信息

Park Nicollet Osteoporosis Center, Section of Rheumatology, Park Nicollet Clinic, Minneapolis, MN 55416, USA.

出版信息

J Clin Densitom. 2002 Fall;5(3):239-46. doi: 10.1385/jcd:5:3:239.

Abstract

The presence of a vertebral compression fracture has been demonstrated to be a predictor of future fracture independent of bone mineral density in prospective cohort studies. Fan-beam densitometers are now available that can image the thoracic and lumbar spines and detect deformities consistent with fracture. We report a pilot study of 342 patients referred for bone densitometry who had lateral vertebral imaging performed. Fifty patients (14.6%) of the entire cohort had one or more vertebral deformities identified on lateral vertebral imaging. Seventy-three patients (21.3%) of the entire cohort were 60 or more years of age and had osteopenia by World Health Organization (WHO) criteria (T-score: -1.0 to -2.4 at the spine, total hip, or femoral neck). Twenty of these patients (27.4%) had one or more vertebral deformities. Without identifying prevalent vertebral deformities, these individuals at high risk for fracture may not be offered pharmacologic therapy to reduce fracture risk. Therefore, it may be reasonable to obtain lateral vertebral imaging at least for individuals age > or =60 yr who have mild to moderate bone loss at the spine or hip.

摘要

在前瞻性队列研究中,已证实椎体压缩性骨折的存在是未来骨折的一个预测指标,与骨矿物质密度无关。现在有扇束骨密度仪,能够对胸椎和腰椎进行成像,并检测出与骨折相符的畸形。我们报告了一项对342例因骨密度测定而转诊且进行了椎体侧位成像的患者的初步研究。在整个队列中,有50例患者(14.6%)在椎体侧位成像中发现有一处或多处椎体畸形。整个队列中有73例患者(21.3%)年龄在60岁及以上,根据世界卫生组织(WHO)标准诊断为骨质减少(脊柱、全髋或股骨颈的T值为-1.0至-2.4)。其中20例患者(27.4%)有一处或多处椎体畸形。如果不识别现患椎体畸形,这些骨折高危个体可能无法获得药物治疗以降低骨折风险。因此,至少对于年龄≥60岁、脊柱或髋部有轻度至中度骨质流失的个体,进行椎体侧位成像可能是合理的。

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