Regös E, Horvath K, Varga S
Ann Immunol Hung. 1975;18:249-54.
A determining time factor in the course of sterilization in autoclaves is the time required for killing microorganisms. Damaging of microorganisms takes its course as an exponential function of time. Taking into account this fact, the parameters of sterilization are determined by the technical standards of the equipment used for autoclaving. The authors present the sterilization problems of infusion solutions, with special regard to the sterilization conditions of heat labile preparations. The results of experiments carried out with autoclaves of different technical standards are discussed.
高压灭菌过程中的一个决定性时间因素是杀灭微生物所需的时间。微生物的损伤过程是时间的指数函数。考虑到这一事实，灭菌参数由用于高压灭菌的设备的技术标准决定。作者介绍了输液溶液的灭菌问题，特别关注热不稳定制剂的灭菌条件。讨论了使用不同技术标准的高压灭菌器进行的实验结果。
