Abrams Robert C, Lachs Mark, McAvay Gail, Keohane Denis J, Bruce Martha L
Weill Medical College of Cornell University, New York Presbyterian Hospital-Cornell University Medical Center, Box 140, 525 E. 68th Street, New York, NY 10021, USA.
Am J Psychiatry. 2002 Oct;159(10):1724-30. doi: 10.1176/appi.ajp.159.10.1724.
The study assessed the contribution of depressive symptoms and cognitive impairment to the prediction of self-neglect in elderly persons living in the community.
Data were drawn from the New Haven Established Populations for Epidemiologic Studies of the Elderly cohort, which included 2,812 community residents age 65 years and older in 1982. The principal outcome examined was the incidence of self-neglect, corroborated by the state's investigation, during 9 years of follow-up (1982-1991).
Among the 2,161 subjects included in the analysis, 92 corroborated cases of self-neglect occurred from 1982 to 1991. The prevalence of clinically significant depressive symptoms at baseline (score > or=16 on the Center for Epidemiologic Studies Depression Scale [CES-D]) was 15.4%, and the prevalence of clinically significant cognitive impairment (four or more errors on the Pfeiffer Short Portable Mental Status Questionnaire) was 7.5%. Subjects with clinically significant depressive symptoms and/or cognitive impairment were more likely than others to experience self-neglect. Clinically significant depressive symptoms and cognitive impairment remained significant predictors of self-neglect in a multivariate model that included age, gender, race, and income. A final model for self-neglect constructed with stepwise selection of risk factors included depressive symptoms and cognitive impairment, as well as male gender, older age, income less than $5,000 per year, living alone, history of hip fracture, and history of stroke.
Elderly individuals living in the community who experience clinically significant depressive symptoms and/or cognitive impairment may be at risk for the development of self-neglect and may become candidates for intervention.
本研究评估了抑郁症状和认知障碍对社区老年人群自我忽视预测的作用。
数据取自纽黑文老年流行病学研究既定人群队列,该队列在1982年纳入了2812名65岁及以上的社区居民。主要研究的结局是在9年随访期(1982 - 1991年)内,经该州调查证实的自我忽视发生率。
在纳入分析的2161名受试者中,1982年至1991年期间有92例经证实的自我忽视病例。基线时具有临床意义的抑郁症状(流行病学研究中心抑郁量表[CES - D]得分≥16)患病率为15.4%,具有临床意义的认知障碍( Pfeiffer简易便携式精神状态问卷错误达4项或更多)患病率为7.5%。具有临床意义的抑郁症状和/或认知障碍的受试者比其他人更易出现自我忽视。在纳入年龄、性别、种族和收入的多变量模型中,具有临床意义的抑郁症状和认知障碍仍是自我忽视的显著预测因素。通过逐步选择危险因素构建的自我忽视最终模型包括抑郁症状、认知障碍,以及男性、高龄、年收入低于5000美元、独居、髋部骨折史和中风史。
社区中出现具有临床意义的抑郁症状和/或认知障碍的老年人可能有发生自我忽视的风险,可能成为干预对象。