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兔实验性淀粉样变肾小球中的纤维性长间距型胶原纤维

Fibrous long spacing type collagen fibrils in the glomeruli of experimental amyloidosis in rabbit.

作者信息

Kimura K, Koizumi F, Kihara I, Kitamura S

出版信息

Lab Invest. 1975 Mar;32(3):279-85.

PMID:123611
Abstract

Fibrous long spacing type collagen fibrils were observed in the glomeruli of experimental amyloidosis induced by either injections of casein or prolonged sensitization of Arthus type tissue antigens in the rabbit. These fibrous long spacing type fibrils were admixed with amyloid fibrils which accumulated both in nodular and diffuse deposition, but they were observed also in irregularly thickened capillary basement membranes and mesangial areas, where amyloid did not deposit. The periodicity of these fibrous long spacing fibrils was approximately 1200 , and nine symmetrical intraperiodic bands were obviously discerned within each period.

摘要

在通过向兔子注射酪蛋白或对其进行Arthus型组织抗原的长期致敏诱导的实验性淀粉样变性的肾小球中观察到了纤维状长间距型胶原纤维。这些纤维状长间距型纤维与以结节状和弥漫性沉积形式积聚的淀粉样纤维混合存在,但在淀粉样物质未沉积的不规则增厚的毛细血管基底膜和系膜区也观察到了它们。这些纤维状长间距纤维的周期约为1200 ,并且在每个周期内明显可辨别出九条对称的周期内带。

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引用本文的文献

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Type VI collagen in extracellular, 100-nm periodic filaments and fibrils: identification by immunoelectron microscopy.细胞外100纳米周期性细丝和原纤维中的VI型胶原蛋白:通过免疫电子显微镜鉴定。
J Cell Biol. 1986 Aug;103(2):393-404. doi: 10.1083/jcb.103.2.393.
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Filamentous aggregates of collagen. Ultrastructural evidence for collagen-fibril degradation in situ.胶原纤维状聚集体。原位胶原纤维降解的超微结构证据。
Arch Dermatol Res. 1985;277(3):214-9. doi: 10.1007/BF00404319.
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Characterization of the collagen in the hexagonal lattice of Descemet's membrane: its relation to type VIII collagen.
Descemet膜六边形晶格中胶原蛋白的特征:其与VIII型胶原蛋白的关系。
J Cell Biol. 1990 Jan;110(1):219-27. doi: 10.1083/jcb.110.1.219.
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[So-called fibrous long-spacing collagen in a murine osteosarcoma (author's transl) ].[小鼠骨肉瘤中所谓的纤维性长间距胶原(作者译)]
Virchows Arch A Pathol Anat Histol. 1976 May 3;370(2):177-83. doi: 10.1007/BF00430813.
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[Banded filamentous associates in the intra- and extracellular space in connection with collagen degradation (author's transl)].与胶原降解相关的细胞内和细胞外空间中的带状丝状缔合物(作者译)
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