Scanton Elizabeth, Stubbs Nikki
Tissue Viability, Leeds North West Primary Care Trust, St Mary's House, Leeds.
Br J Community Nurs. 2002 Sep:8, 10, 12, passim.
The use of antiseptics for wound care has long been controversial. Antiseptics have a broad spectrum of activity that, in addition to making them effective against a broad range of microorganisms, makes them toxic to living human tissue. Consequently antiseptics gradually fell out of favour following the introduction of systemic antibiotics. In recent years, however, there has been renewed interest in antiseptics as a result of the evolution of antibiotic-resistant bacteria, and considerable funds are being invested in the development of modern antiseptic dressings. This article aims to discuss some of these issues and set them in a practical context so that readers recognize the complexities of decision-making where antiseptics are concerned. This in turn should enable them to make a better-informed choice for their patients or, where appropriate, seek expert advice.
长期以来，在伤口护理中使用防腐剂一直存在争议。防腐剂具有广泛的活性谱，这不仅使它们对多种微生物有效，也使其对人体活组织有毒性。因此，随着全身用抗生素的引入，防腐剂逐渐失宠。然而，近年来，由于抗生素耐药菌的出现，人们对防腐剂重新产生了兴趣，并且大量资金正投入到现代抗菌敷料的研发中。本文旨在讨论其中的一些问题，并将它们置于实际背景中，以便读者认识到在涉及防腐剂时决策的复杂性。这反过来应能使他们为患者做出更明智的选择，或者在适当情况下寻求专家建议。
