Potvliege P R, De Roy G, Dupuis F
J Clin Pathol. 1975 Nov;28(11):891-8. doi: 10.1136/jcp.28.11.891.
The necropsy reports and clinical observations of 44 cases of glomerulonephritis occurring in patients over 55 years old were reviewed. Two-thirds of the patients died from a rapidly progressive renal disease with focal necrotizing and fibrosing glomerular lesions; half of these exhibited a granulomatous splenic trabeculitis; an associated vasculitis was found in only a minority of these cases. Another important group consisted of cases of acute diffuse glomerulonephritis which, as a rule, occurred in association with a major infection. There were only four cases of chronic sclerosing glomerulonephritis.
回顾了44例55岁以上患者发生的肾小球肾炎的尸检报告和临床观察结果。三分之二的患者死于快速进展性肾病，伴有局灶性坏死和纤维化肾小球病变；其中一半表现为肉芽肿性脾小梁炎；这些病例中只有少数发现有相关的血管炎。另一个重要的组由急性弥漫性肾小球肾炎病例组成，通常与一次重大感染有关。慢性硬化性肾小球肾炎仅有4例。
