细胞分辨率下的小鼠大脑转录组图谱。
A transcriptome atlas of the mouse brain at cellular resolution.
作者信息
Carson James P, Thaller Christina, Eichele Gregor
机构信息
Program in Structural and Computational Biology and Molecular Biophysics and National Center for Macromolecular Imaging, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.
出版信息
Curr Opin Neurobiol. 2002 Oct;12(5):562-5. doi: 10.1016/s0959-4388(02)00356-2.
A genome-wide expression atlas of the nervous system at cellular resolution would be a valuable resource for neurobiology, genetics, developmental biology and medicine. Progress in automation of in situ hybridization makes such an atlas possible. Standardized and computerized annotation of expression patterns will be critical for producing a searchable atlas database that can be accessed through the internet.
一个具有细胞分辨率的全基因组神经系统表达图谱将成为神经生物学、遗传学、发育生物学和医学的宝贵资源。原位杂交自动化技术的进展使这样一个图谱成为可能。对表达模式进行标准化和计算机化注释对于生成一个可通过互联网访问的可搜索图谱数据库至关重要。
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